Reduce AIDS drug toxicity and side effects

 Posted by on June 12, 2015 at 7:08 am
Jun 122015
 
Reduce AIDS drug toxicity and side effects

I embarked on my third course of ARVs since 1998. For ten of the sixteen years I have been HIV-positive, I was able to manage well enough without ARVs and I continue to believe there is no reason for otherwise healthy HIV-positive—let alone negative—gay men to take these drugs. To those who want to wave a recent study about the benefits of early intervention in my face, I would ask them why they put so much faith in a science that has utterly failed us to date.

The truth about Truvada: PrEP won’t stop AIDS

 Posted by on December 1, 2014 at 4:56 am
Dec 012014
 
The truth about Truvada: PrEP won’t stop AIDS

I’m willing to grant that gay men are entitled to use PrEP… provided they have access to all the information they need to make an informed decision. Informed consent has been a hallmark of the HIV and AIDS research and prevention efforts for three decades, and that shouldn’t be waived for the campaign favoring PrEP.

Gay men deserve to know that all the claims for Truvada reducing the risk of acquiring HIV-positivity  are based on trials—funded by Gilead—that emphasized the importance of using condoms…

Dr. Jacques Leibowitch: 4 days a week is enough!

 Posted by on May 5, 2014 at 6:41 am
May 052014
 
Dr. Jacques Leibowitch: 4 days a week is enough!

In the simplest possible summation, Leibowitch has been treating HIV-positive patients with traditional ARV cocktails, called HAART. Where he leaves the path of traditional treatment guidelines is that once a patient is “stabilised”—meaning they have achieved respectably high CD4 counts, and their viral load is undetectable for six months—Leibowitch starts reducing the number of days per week that a patient takes these drugs, to as little as twice per week.

Higher CD4 count increases risk of ARV adverse effects

 Posted by on March 1, 2014 at 9:02 am
Mar 012014
 
Higher CD4 count increases risk of ARV adverse effects

Each patient fell into one of three groups: <350 CD4 cells/muL; 351-499; and >500. This last group would be considered “normal” according to AIDS.gov, which lists the range for CD4 counts as 500-1000. Yet, according to this study, this group of so-called “healthy” patients were almost one and a half times more likely to experience a drug-related adverse effect.

The report reinforces another point that I find I must continue to drive home over and over again, and that is the definition of “low CD4 counts”.

Did Gos Blank die of AIDS? – UPDATED

 Posted by on January 13, 2014 at 5:10 pm
Jan 132014
 
Did Gos Blank die of AIDS? - UPDATED

So, did Gos Blank die of AIDS? That was the original question, was it not? That is what both AIDS dissidents and the AIDS apologist trolls are waiting to hear, isn’t it?

I don’t know how it is possible to come to any conclusion that would satisfy both sides. Any answer given would only raise more questions, though not many new ones, really. Before anyone starts dancing on Gos’ grave, let’s examine some of these questions… in Gos’ own words as much as possible. (Unless noted otherwise, all blockquotes from this point on are from Gos’ book)

AIDS drugs: when resistance is futile

 Posted by on December 17, 2013 at 11:07 am
Dec 172013
 
AIDS drugs: when resistance is futile

In nearly every conversation I’ve had with Affecteds who are experimenting with ways to reduce the toxicity of antiretroviral (ARV) regimens, questions about “AIDS drug resistance” comes up. Resistance is often raised as a boogeyman in research trials of monotherapy and intermittent treatment options. While drug resistance—especially bacterial antibiotic resistance to staphylococcus or tuberculosis, for example—is increasingly a problem in modern medicine, one is unlikely to hear drug resistance discussed quite the way it is with AIDS. No other pathogen is described as “sneaky”, “clever”, or more mutable than HIV, despite the fact that retroviruses do not even meet most definitions for being a living entity, let alone have a brain.

AIDS drug guidelines: Stop the nukes!

 Posted by on December 13, 2013 at 11:06 pm
Dec 132013
 
AIDS drug guidelines: Stop the nukes!

Stop the nukes! No, not nuclear weapons. Well, yes, those too, but today I’m writing about the increase in reports I’m seeing from the AIDS drug medical literature calling for an end to the use of nucleoside(tide) reverse transcriptase inhibitors (NRTIs), not-so-ironically referred to as “nukes”. As I have written previously, there have been rumblings from clinicians and researchers in the medical literature since at least 2010 to get rid of the NRTI class of antiretroviral drugs entirely from treatment guidelines.

Unfortunately, it is unlikely that this change will occur at anything comparable to the speed with which AZT and other poison pills were “fast-tracked” to market more than 25 years ago.

Checking in: quit ARV drugs again

 Posted by on July 5, 2013 at 8:34 am
Jul 052013
 
Checking in: quit ARV drugs again

Gawd forbid this period of inactivity be mistaken as some sort of ill omen. What I can say is that I’m alive and doing well by most measures that matter. I am struggling with fatigue, and depression, which may help explain my absence online.

I quit the low-dose darunavir monotherapy on May 29, almost exactly one year after I had restarted ARVs. I am satisfied with, if not excited about the “numbers”, which I will update in a future post, along with additional news about my health and medical status.